Co-receptors

List of co-receptors for type I receptors and brief comment, e.g. inhibitor or promotor of BMP signaling, protein family.

* Betaglycan - stimulating
* Endoglin - stimulating
* RGMa - stimulating
* RGMb (Dragon) - stimulating
* RGMc - stimulating
* Ror2 - inhibitory

List of co-Receptors for type II receptors and brief comment, e.g. inhibitor or promotor of BMP signaling, protein family.

* BAMBI - inhibitory
* c-Kit - stimulating
* RGMb (Dragon) - stimulating
* TrkC - inhibitory

Separate subpage for each of the co-receptors with detailed description of the protein and how it affects BMP signaling, see list below.

Figure_3A.png

BMP receptor interactome. BMP receptors BRI (left) and BRII (right) are positively (+) and negatively () regulated by many different co-receptors. These are either GPI-anchored (1), have very short cytosolic parts (2) or they are receptor tyrosine kinases (RTK; 3). On the intracellular side the receptors interact with proteins that contribute to receptor regulation and finetuning or progression of receptor signaling [Sieber, 2009].

Unless otherwise stated, the content of this page is licensed under Creative Commons Attribution-ShareAlike 3.0 License